Time Session
DAY 1 – 14 October 2019  
7:00-9:00 am Registration, Continental Breakfast
8:00-8:45 am Sunrise Session
Kenneth Waterman, FreeThink Technologies (US)
ASAPprime® and the science of highly accelerated aging
Session I  
8:50-8:55 am Accelerated Stability Modeling
Kenneth Waterman, FreeThink Technologies (US)
Conference Welcome
8:55-9:00 am Session Chair
Introduction to Session
9:00-9:40 am Sara Vrielynck, Galapagos NV (Belgium)
Introducing ASAP into a new company
9:40-10:20 am Sabine Thielges, Novartis (Switzerland)
ASAP for parenteral formulation development – solution and lyophilisate
10:20-11:00 am Morning Break
11:00-11:40 pm Kenneth Waterman, FreeThink Technologies (US)
Accelerated stability modeling for difficult products: when nothing happens and when degradants degrade
11:40-12:20 pm Els van Deventer-Troost, Janssen Pharmaceuticals (Belgium)
Experience of applying Arrhenius modeling and alternatives to adenoviruses
12:20-1:30 pm Lunch
1:30-2:10 pm Hana Prokopcova, Janssen Pharmaceuticals (Belgium)
Topic TBD (IQ Speaker, Modeling Group)
2:10-2:50 pm Elke Debie, Janssen Pharmaceuticals (Belgium)
Feedback from the Regulatory Sub-team of the Risk-based Predictive Stability IQ Group
2:50-3:30 pm Afternoon Break
3:30-4:10 pm Graeme Horne, Summit Therapeutics (UK)
Stability Modeling of Amorphous Dispersions
4:10-4:50 pm Matjaz Boncina, University of Ljubljana (Slovenia) Prediction of stability of biologics in solution
4:50-4:55 pm Wrap up of Day 1
5:00-6:30pm FreeThink-sponsored Networking Event/Exhibitor Expo
   

 
 
DAY 2 – 15 October 2019  
Session II  
8:30-8:35 am Forced Degradation and the Chemistry of Degradation
Session Chair
Introduction to Session
8:35-9:05 am Ash Ali, Lhasa Ltd (UK)
Zeneth knowledge-based system for the prediction of forced degradation of organic compounds
9:05-9:45 am Kausik Nanda, Merck (US)
Enrichment of relevant oxidative degradation products in pharmaceuticals with targeted chemoselective oxidation
9:45-10:15 am Morning Break
10:15-10:55 am Steve Baertschi, Baertschi Consulting (US)
Drug photostability: the science and application of photo-produced reactive oxygen species
10:55-11:40 pm David Elder (UK)
Mutagenic degradation products- prediction, assessment, control
11:40-12:15 pm Lunch
12:15-1:00 pm Poster session
Session III  
1:00-1:05 pm Packaging and Stability
Session Chair
Introduction to Session
1:05-1:45 pm Helen Williams, AstraZeneca (UK)
Applications of packaging predictions
1:45-2:10 pm Thomas Dries, Honeywell (Germany)
Protective blister packaging materials: Aclar
2:10-2:35 pm Daniel Stagnaro, Klöckner-Pentaplast (US)
Using finite element analysis to determine blister permeability from tooling design
2:35-3:05 pm Afternoon Break
Session IV  
3:05-3:10 pm Stability Science Frontiers
Session Chair
Introduction to Session
3:10-3:50 pm Garry Scrivens, Pfizer (UK)
Effect of drug load/particle size/surface area on degradation rates in solids
3:50-4:30 pm Malin Suurkuusk, TA Instruments (Sweden) Isothermal Microcalorimetry for Pharmaceutical Stability Assessment
4:30-5:10 pm Steven Brown, Warwick University (UK)
Solid-state NMR to understand pharmaceutical stability
5:10-5:15 pm Conference Wrap Up