3rd Annual Conference 2017
3rd – 5th October 2017
Crowne Plaza Hotel – Blanchardstown, Dublin, Ireland

Stress Testing in Solid State: Towards a Realistic Degradation Profile

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Stress Testing in Solid State: Towards a Realistic Degradation Profile

Stress Testing in Solid State: Towards a Realistic Degradation Profile

Peter Persich, Ph.D.
Scientist, Janssen Pharmaceuticals (J & J)
Beerse, Belgium

Stress testing is an important and convenient tool to predict degradation profiles and to understand drug decomposition processes. A thoroughly assessed degradation profile allows the smooth development of stability indicating methods, robust formulations, and overall control strategies. In this respect, the selection of adequate and conclusive forced degradation conditions is one of the major challenges. The presented case studies will exemplify general strategies as well as novel approaches to study degradation pathways and to obtain realistic degradation profiles.